UCSF Pharmacogenetics of Membrane Transporters
Experiment View
NM_004790
NM_153276
NM_153277
NM_153278
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Transcript:NM_004790 [Chr.11(-): 62744069-62752495 GRCh37]
Id:SLC22A6_exon4
Position:Chr.11(-): 62749158-62749615 GRCh37
Chr.11(-): 62505734-62506191 NCBI36
Sequence:
ACCCTGGCACTCAACTTACTCGATGCATTTTCCACTGAGCCTTGGGACAGGCCAAGGTTTGGATGGAGGGAGGGGCCTTT
ACTAGCCCAGCAGCCCAGGTAGTTGCAGCATCCTGTCTTAACCCTCTTTCCAGATGTGGAGTGGATGCCCATTCACACAC
GGGCCTGCGTGGGCACCTTGA
TTGGCTATGTCTACAGCCTGGGCCAGTTCCTCCTGGCTGGTGTGGCCTACGCTGTGCCC
CACTGGCGCCACCTGCAGCTACTGGTCTCTG
CGCCTTTTTTTGCCTTCTTCATCTACTCCTGGTGCGTGGGGCCTAGGGT
TGGAGGTGGTTGCCACAGGAGCCCAGAGGCTGCAAGGGACAGGACATCTCCCAGAGCTCAGCACACATCCCATCCCACAA
ATGTAGAGAAGGTCAAACCCAGTCCAATGCCTCTGTGTGACAGATAGGGAAACCAAGG
Color Legend: SNP  UTR  CODING
Sample Sets: Set-II
Assays: SLC22A6_4_PCR
PMT impact: P - Public  D - Discovered  E - Exclusive  (dbSNP build 142)
Array availability: I - found on Illumina Human1M-Duo BeadChip (2011-04-21)  A - found on Affymetrix Genome-Wide SNP Array 6.0 (2011-06-21)  
FeaturePMT IDdbSNP/ PubMedArray AvailabilityGenomic PositionTranscript PositionCoding PositionNucleotide ChangeStrandAmino Acid PositionAmino Acid ChangeStatisticsAA FreqCA FreqAS FreqME FreqPA FreqSample Set
 
4701
PDE
A
62749590 GRCh37
62506166 NCBI36
  
ACCCTGGCACTCAACTTACTCGATG C → T ATTTTCCACTGAGCCTTGGGACAGG
- 
 
n=
C/C=
C/T=
T/T=
T=
158
75
4
0
0.025
160
68
12
0
0.075
118
57
2
0
0.017
100
48
2
0
0.020
12
6
0
0
0.000
Set-II
 
4702
PDE
A
62749494 GRCh37
62506070 NCBI36
  
AGGTAGTTGCAGCATCCTGTCTTAA C → T CCTCTTTCCAGATGTGGAGTGGATG
- 
 
n=
C/C=
C/T=
T/T=
T=
160
60
18
2
0.138
160
80
0
0
0.000
120
60
0
0
0.000
100
50
0
0
0.000
12
6
0
0
0.000
Set-II
Exon 4: Coding
4703
PDE
I
62749434 GRCh37
62506010 NCBI36
1010677
ACACGGGCCTGCGTGGGCACCTTGA T → C TGGCTATGTCTACAGCCTGGGCCAG
-226
Ile → Thr
(D=89)
n=
T/T=
T/C=
C/C=
C=
160
80
0
0
0.000
160
79
1
0
0.006
120
60
0
0
0.000
100
50
0
0
0.000
12
6
0
0
0.000
Set-II
Exon 4: Coding
4704
PDE
I
62749344 GRCh37
62505920 NCBI36
1100767
CGCCACCTGCAGCTACTGGTCTCTG C → T GCCTTTTTTTGCCTTCTTCATCTAC
-256
Ala → Val
(D=64)
n=
C/C=
C/T=
T/T=
T=
160
79
1
0
0.006
160
80
0
0
0.000
120
60
0
0
0.000
100
50
0
0
0.000
12
6
0
0
0.000
Set-II

Transmembrane prediction:

Non-synonymous amino acid changes shown in red, indels (insertions and deletions) in blue, and synonymous changes in green. Exon(s) indicated by black outlines.