UCSF Pharmacogenetics of Membrane Transporters
Experiment View
NM_000927
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Transcript:NM_000927 [Chr.7(-): 87133179-87342639 GRCh37]
Id:ABCB1_exon8
Position:Chr.7(-): 87190505-87190768 GRCh37
Chr.7(-): 87028441-87028704 NCBI36
Sequence:
TTTTACTTTACAAAAGATAAAATTAACGTGTTTTTTTCATGATCCAAAATTGTATTTTTAAACAGATACTATCTTCATTT
ACTGATAAAGA
ACTCTTAGCGTATGCAAAAGCTGGAGCAGTAGCTGAAGAGGTCTTGGCAGCAATTAGAACTGTGATTGC
ATTTGGAGGACAAAAGAAAGAACTTGAAAG
GTTTGAGTTTCTTTTTTAAATGGATAGATATGTTAAATTCTGTCTTCTCA
AATGCCCTTCAGATTGACAGTGTT
Color Legend: SNP  UTR  CODING
Sample Sets: Set-I
Assays: ABCB1_8_PCR
PMT impact: P - Public  D - Discovered  E - Exclusive  (dbSNP build 142)
Array availability: I - found on Illumina Human1M-Duo BeadChip (2011-04-21)  A - found on Affymetrix Genome-Wide SNP Array 6.0 (2011-06-21)  
FeaturePMT IDdbSNP/ PubMedArray AvailabilityGenomic PositionTranscript PositionCoding PositionNucleotide ChangeStrandAmino Acid PositionAmino Acid ChangeStatisticsAA FreqCA FreqAS FreqME FreqPA FreqSample Set
Exon 9: Coding
3683
PDE
I
87190677 GRCh37
87028613 NCBI36
1222729
TACTATCTTCATTTACTGATAAAGA A → G CTCTTAGCGTATGCAAAAGCTGGAG
-243
Glu = Glu
n=
A/A=
A/G=
G/G=
G=
200
100
0
0
0.000
200
99
1
0
0.005
60
30
0
0
0.000
20
10
0
0
0.000
14
7
0
0
0.000
Set-I
Exon 9: Coding
3684
PDE
87190625 GRCh37
87028561 NCBI36
1274781
AGTAGCTGAAGAGGTCTTGGCAGCA A → G TTAGAACTGTGATTGCATTTGGAGG
-261
Ile → Val
(D=29)
n=
A/A=
A/G=
G/G=
G=
200
97
3
0
0.015
200
100
0
0
0.000
60
30
0
0
0.000
20
10
0
0
0.000
14
7
0
0
0.000
Set-I

Transmembrane prediction:

Non-synonymous amino acid changes shown in red, indels (insertions and deletions) in blue, and synonymous changes in green. Exon(s) indicated by black outlines.