UCSF Pharmacogenetics of Membrane Transporters
Experiment View
NM_000927
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Transcript:NM_000927 [Chr.7(-): 87133179-87342639 GRCh37]
Id:ABCB1_exon18
Position:Chr.7(-): 87170614-87170840 GRCh37
Chr.7(-): 87008550-87008776 NCBI36
Sequence:
CAGGTCCAGGATGGGTTCTTCACTGATTGAACTAAAAATCCTTTAAATGTTTTCTCACAGGTTTTTACAAGAATTGATGA
TCCTGAAACAAAACGACAGAATAGTAACTTGTTTTCACTATTGTTTCTAGCCCTTGGAATTATTTCTTTTATTACATTTT
TCCTTCAG
GTAAATGTTTCCATTTTCACTATATTCATTTTGAGAAATGCATCATTATTCAACTGGGG
Color Legend: SNP  UTR  CODING
Sample Sets: Set-I
Assays: ABCB1_18_DHPLC
ABCB1_18_PCR
PMT impact: P - Public  D - Discovered  E - Exclusive  (dbSNP build 142)
Array availability: I - found on Illumina Human1M-Duo BeadChip (2011-04-21)  A - found on Affymetrix Genome-Wide SNP Array 6.0 (2011-06-21)  
FeaturePMT IDdbSNP/ PubMedArray AvailabilityGenomic PositionTranscript PositionCoding PositionNucleotide ChangeStrandAmino Acid PositionAmino Acid ChangeStatisticsAA FreqCA FreqAS FreqME FreqPA FreqSample Set
 
3693
PDE
I
87170807 GRCh37
87008743 NCBI36
  
GGATGGGTTCTTCACTGATTGAACT A → G AAAATCCTTTAAATGTTTTCTCACA
- 
 
n=
A/A=
A/G=
G/G=
G=
200
99
1
0
0.005
200
98
2
0
0.010
60
30
0
0
0.000
20
9
1
0
0.050
14
7
0
0
0.000
Set-I

Transmembrane prediction:

Non-synonymous amino acid changes shown in red, indels (insertions and deletions) in blue, and synonymous changes in green. Exon(s) indicated by black outlines.