UCSF Pharmacogenetics of Membrane Transporters
Experiment View
NM_000927
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Transcript:NM_000927 [Chr.7(-): 87133179-87342639 GRCh37]
Id:ABCB1_exon20
Position:Chr.7(-): 87165704-87165918 GRCh37
Chr.7(-): 87003640-87003854 NCBI36
Sequence:
TCTTGGAGCTGAGAGTCTCATAAACAGCTTTAAGGTAATAAAATCATTTTCTGTGCCACAGGATGTGAGTTGGTTTGATG
ACCCTAAAAACACCACTGGAGCATTGACTACCAGGCTCGCCAATGATGCTGCTCAAGTTAAAGGG
GTACGTGCCTCCTTT
CTACTGGTGTTTGTCTTAATTGGCCATTTTGGACCCCAGCATGAAACTAATTTTC
Color Legend: SNP  UTR  CODING
Sample Sets: Set-I
Assays: ABCB1_20_PCR
PMT impact: P - Public  D - Discovered  E - Exclusive  (dbSNP build 142)
Array availability: I - found on Illumina Human1M-Duo BeadChip (2011-04-21)  A - found on Affymetrix Genome-Wide SNP Array 6.0 (2011-06-21)  
FeaturePMT IDdbSNP/ PubMedArray AvailabilityGenomic PositionTranscript PositionCoding PositionNucleotide ChangeStrandAmino Acid PositionAmino Acid ChangeStatisticsAA FreqCA FreqAS FreqME FreqPA FreqSample Set
 
3694
PDE
87165766 GRCh37
87003702 NCBI36
  
GCTGCTCAAGTTAAAGGGGTACGTG C → G CTCCTTTCTACTGGTGTTTGTCTTA
- 
 
n=
C/C=
C/G=
G/G=
G=
200
99
1
0
0.005
198
99
0
0
0.000
60
30
0
0
0.000
20
10
0
0
0.000
14
7
0
0
0.000
Set-I
 
2870
PDE
3 pubsIA
87165750 GRCh37
87003686 NCBI36
  
GGGTACGTGCCTCCTTTCTACTGGT G → A TTTGTCTTAATTGGCCATTTTGGAC
- 
 
n=
G/G=
G/A=
A/A=
A=
200
73
24
3
0.150
198
76
22
1
0.121
60
26
4
0
0.067
20
6
4
0
0.200
14
7
0
0
0.000
Set-I
 
3695
PDE
IA
87165734 GRCh37
87003670 NCBI36
  
TCTACTGGTGTTTGTCTTAATTGGC C → T ATTTTGGACCCCAGCATGAAACTAA
- 
 
n=
C/C=
C/T=
T/T=
T=
200
93
7
0
0.035
198
99
0
0
0.000
60
30
0
0
0.000
20
10
0
0
0.000
14
7
0
0
0.000
Set-I

Transmembrane prediction:

Non-synonymous amino acid changes shown in red, indels (insertions and deletions) in blue, and synonymous changes in green. Exon(s) indicated by black outlines.