| Common Name: | ABC27,ABC50 |
| HGNC Symbol: | ABCF1 |
| HGNC Description: | ATP-binding cassette, sub-family F (GCN20), member 1 |
| HGNC ID: | 70 |
| Chromosome: | Chr.6(+): 30647149-30667288 |
| Location: | 6p21.33 |
| OMIM: | 603429 |
| OMIM Phenotype: | None |
| Accessions: | AF027302 |
| Nucleotide RefSeq: | NM_001025091 |
| Protein RefSeq: | NP_001020262 |
| Entrez: | 23 |
| Isoforms: | 2 |
| Evidence: | Substrate In Vitro Evidence: No transmembrane domains; Possibly a protein for translation based on yeast homology. - Hydropathy plot. Richard M, et al. Genomics. 1998 Oct 15;53(2):137-45. eIF2 (initiation factor in translation) co-immunoprecipitates with ABCF1 - Tyzack JK, et al. J Biol Chem. 2000 Nov 3;275(44):34131-9. Influences methionyl-tRNA association with eIF2 - Tyzack JK, et al. J Biol Chem. 2000 Nov 3;275(44):34131-9. Tissue Distribution Evidence: TNF(-induced synoviocytes - Differential display PCR. Richard M, et al. Genomics. 1998 Oct 15;53(2):137-45. Trachea, Testis, Uterus > Placenta, Lung, Prostate, Spleen - TaqMan RT-PCR. Langmann T, et al. Clinical Chemistry. 2003; 49: 230-8. |
| Tissues: | Trachea, Testis, Uterus > Placenta, Lung, Prostate, Spleen |
| Type: | protein coding |
| Sets: | 0 |
| PharmGKB ID: | PA24405 |
| HPRD ID: | 09139 |
| Substrates: | euk. Initiation factor 2 (eIF2) as binding partner |
| Trivial Names: | ABC27, ABC50 |
| Transcripts: | NM_001025091 [Chr.6(+): 30647149-30667288] NM_001090 [Chr.6(+): 30647149-30667288] |
View on UCSC Genome Browser or Ensembl Genome Browser
Transmembrane prediction: TOPO2 image is not available.