UCSF Pharmacogenetics of Membrane Transporters
Gene View
Common Name:PXR
HGNC Symbol:NR1I2
HGNC Description:nuclear receptor subfamily 1, group I, member 2
HGNC ID:7968
Superfamily:None
Chromosome:Chr.3(+): 119499331-119552295 GRCh37
Location:3q12-q13.3
OMIM:603065
OMIM Phenotype:None
Accessions:AJ009936
Nucleotide RefSeq:NM_003889
Protein RefSeq:NP_003880
Entrez:8856
Ensembl:ENSG00000144852
Isoforms:4
Evidence:None
Tissues:None
Type:protein-coding
Sets:II
PharmGKB ID:PA378
HPRD ID:04346
Substrates:None
Trivial Names:BXR, PAR, PRR, PXR, SAR, SXR, ONR1, PAR1, PAR2, PARq
Transcripts:NM_003889.3 [Chr.3(+): 119499331-119537332 GRCh37]
NM_022002.2 [Chr.3(+): 119501557-119537332 GRCh37]
NM_033013.2 [Chr.3(+): 119499331-119537332 GRCh37]
XM_005247866.1 [Chr.3(+): 119500879-119552295 GRCh37]
ENST00000337940 [Chr.3(+): 119501557-119537332 GRCh37]
ENST00000393716 [Chr.3(+): 119499331-119537332 GRCh37]
ENST00000466380 [Chr.3(+): 119499331-119537332 GRCh37]
ENST00000474090 [Chr.3(+): 119500882-119529399 GRCh37]
ENST00000493757 [Chr.3(+): 119529923-119537331 GRCh37]
Annotation History:View Events (12)

GTEx Expression by Gene and Transcript

The heat map summarizes relative expression by tissue type at two levels of tissue detail, e.g., 'Brain' and 'Brain - Amygdala'. Choose among four calculated expression values, including mean and median RPKM values, and quantile normalized (QN) distributions of these values. (Note that differences between some distributions are subtle.) The coloring is relative to the mean of all displayed values. All values are log base 2. (See also PMT GTEx Expression Plotting.) Click on a transcript or tissue to resort the data.

Tissues:
Expression values:
No expression data exists for NR1I2.

Variant Data

View all PMT variants for NR1I2 on UCSC Genome Browser
Showing SNP features for transcript:   
1000 Genomes  

20141104 phase 3 variant call set of the 20130502 sequence freeze and alignments for SNPs and short indels (indels > 255 and structural variants are not included here). This variant set contains 2504 individuals from 26 populations (mouse over population column heading for population sizes).
Showing gene variants in regions defined by NCBI RefSeq exons, putative promoter, and PMT resequencing assays.
Note: Frequencies are calculated directly from reported genotypes and may vary from consensus frequencies reported by the 1000 Genomes project, which relied on additional data and the GATK tool Variant Quality Score Recalibrator.
dbSNP build 142.
Array availability: I - found on Illumina Human1M-Duo BeadChip (2011-04-21)  A - found on Affymetrix Genome-Wide SNP Array 6.0 (2011-06-21)  
Download the SNP table data as a tab-delimited file.

Transmembrane prediction: TOPO2 image is not available.