UCSF Pharmacogenetics of Membrane Transporters
Gene View
Common Name:MCT6
HGNC Symbol:SLC16A6
HGNC Description:solute carrier family 16, member 6
HGNC ID:10927
Superfamily:SLC
Chromosome:Chr.17(-): 66263167-66287405 GRCh37
Location:17q24.2
OMIM:603880
OMIM Phenotype:None
Accessions:BC064832
Nucleotide RefSeq:NM_004694
Protein RefSeq:NP_004685
Entrez:9120
Ensembl:ENSG00000108932
Isoforms:4
Evidence:Tissue Distribution Evidence: Muscle, Brain, Pancreas - Review article. Halestrap AP, et al. Pflugers Archives. 2003 (Epub).
Tissues:Muscle, Brain, Pancreas
Type:protein-coding
Sets:0
PharmGKB ID:PA35818
HPRD ID:04857
Substrates:No data
Trivial Names:MCT6, MCT7
Transcripts:NM_004694.4 [Chr.17(-): 66263167-66287405 GRCh37]
NM_001174166.1 [Chr.17(-): 66263167-66287405 GRCh37]
XM_005257789.1 [Chr.17(-): 66263167-66274567 GRCh37]
XM_005277784.1 [Chr.17(-): 327037-338437 GRCh37]
ENST00000327268 [Chr.17(-): 66263167-66287257 GRCh37]
ENST00000580666 [Chr.17(-): 66264338-66287407 GRCh37]
ENST00000582867 [Chr.17(-): 66270189-66287323 GRCh37]
ENST00000583477 [Chr.17(-): 66267769-66287408 GRCh37]
Annotation History:View Events (18)

GTEx Expression by Gene and Transcript

The heat map summarizes relative expression by tissue type at two levels of tissue detail, e.g., 'Brain' and 'Brain - Amygdala'. Choose among four calculated expression values, including mean and median RPKM values, and quantile normalized (QN) distributions of these values. (Note that differences between some distributions are subtle.) The coloring is relative to the mean of all displayed values. All values are log base 2. (See also PMT GTEx Expression Plotting.) Click on a transcript or tissue to resort the data.

Tissues:
Expression values:
No expression data exists for SLC16A6.

Variant Data

View all PMT variants for SLC16A6 on UCSC Genome Browser
Showing SNP features for transcript:   
1000 Genomes  

20141104 phase 3 variant call set of the 20130502 sequence freeze and alignments for SNPs and short indels (indels > 255 and structural variants are not included here). This variant set contains 2504 individuals from 26 populations (mouse over population column heading for population sizes).
Showing gene variants in regions defined by NCBI RefSeq exons, putative promoter, and PMT resequencing assays.
Note: Frequencies are calculated directly from reported genotypes and may vary from consensus frequencies reported by the 1000 Genomes project, which relied on additional data and the GATK tool Variant Quality Score Recalibrator.
dbSNP build 142.
Array availability: I - found on Illumina Human1M-Duo BeadChip (2011-04-21)  A - found on Affymetrix Genome-Wide SNP Array 6.0 (2011-06-21)  
Download the SNP table data as a tab-delimited file.

Transmembrane prediction:

Non-synonymous amino acid changes shown in red, indels (insertions and deletions) in blue, and synonymous changes in green. Exon(s) indicated by black outlines.