| Common Name: | EAAC1 |
| HGNC Symbol: | SLC1A1 |
| HGNC Description: | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| HGNC ID: | 10939 |
| Chromosome: | Chr.9(+): 4480444-4577469 |
| Location: | 9p24 |
| OMIM: | 133550 |
| OMIM Phenotype: | None |
| Accessions: | NM_004170 |
| Nucleotide RefSeq: | NM_004170 |
| Protein RefSeq: | NP_004161 |
| Entrez: | 6505 |
| Isoforms: | 1 |
| Evidence: | Substrate In Vitro Evidence: 1. L-Glu, D/L Asp Substrate In Vivo Evidence: 1. Knockout mice develop dicarboxylic aminoaciduria Peghini P et al, EMBO Journal, 1997: 3822-3832 Tissue Distribution Evidence: 1. Brain (hippocampus, cerebral cortex, olfactory bulb, striatum, superior colliculus and thalamus), small intestine, kidney, liver and heart, RT-PCR, Kanai Y et al, Nature 1992: 467-71 |
| Tissues: | brain, small intestine, liver, kidney, liver, heart |
| Type: | protein coding |
| Sets: | V |
| PharmGKB ID: | PA35826 |
| HPRD ID: | 00597 |
| Substrates: | L-Glu, D/L Asp |
| Trivial Names: | EAAC1, EAAT3 |
| Transcripts: | NM_004170 [Chr.9(+): 4480444-4577469] |
View on UCSC Genome Browser or Ensembl Genome Browser
Transmembrane prediction:
Non-synonymous amino acid changes shown in red, indels (insertions and deletions) in blue, and synonymous changes in green. Exon(s) indicated by black outlines.