| Common Name: | EAAT4 |
| HGNC Symbol: | SLC1A6 |
| HGNC Description: | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
| HGNC ID: | 10944 |
| Chromosome: | Chr.19(-): 14921991-14944730 |
| Location: | 19p13.12 |
| OMIM: | 600637 |
| OMIM Phenotype: | None |
| Accessions: | NM_005071 |
| Nucleotide RefSeq: | NM_005071 |
| Protein RefSeq: | NP_005062 |
| Entrez: | 6511 |
| Isoforms: | 1 |
| Evidence: | Substrate In Vitro Evidence: Glutamate Aspartate - Xenopus oocytes expressing EAAT4. Fairman WA, et al. Nature. 1995; 375: 599-603. Substrate In Vivo Evidence: Neurotransmitters - RNA interference in rats develop ataxia. Maragakis N, et al. 1997. Neurosci. Meeting Abstr. 23, 585.2. Tissue Distribution Evidence: Brain (mouse and cat) - RT-PCR, Immunocytochem., Western Blot. Massie A, et al. Neuroreport. 2001; 12: 393-7. Brain (cerebellum) - Furuta A, et al. Neuroscience. 1997 Dec;81(4):1031-42. |
| Tissues: | Brain |
| Type: | protein coding |
| Sets: | V |
| PharmGKB ID: | PA35831 |
| HPRD ID: | 09005 |
| Substrates: | Glutamate, Asparate, Neurotransmitters |
| Trivial Names: | EAAT4, MGC33092, MGC43671 |
| Transcripts: | NM_005071 [Chr.19(-): 14921991-14944730] |
View on UCSC Genome Browser or Ensembl Genome Browser
Transmembrane prediction:
Non-synonymous amino acid changes shown in red, indels (insertions and deletions) in blue, and synonymous changes in green. Exon(s) indicated by black outlines.