UCSF Pharmacogenetics of Membrane Transporters
Gene View
Common Name:SLC26A11
HGNC Symbol:SLC26A11
HGNC Description:solute carrier family 26 (anion exchanger), member 11
HGNC ID:14471
Superfamily:SLC
Chromosome:Chr.17(+): 78194200-78227308 GRCh37
Location:17q25.3
OMIM:610117
OMIM Phenotype:None
Accessions:BC035900
Nucleotide RefSeq:NM_173626
Protein RefSeq:NP_775897
Entrez:284129
Ensembl:ENSG00000181045
Isoforms:5
Evidence:Substrate In Vitro Evidence: Expression in Sf9 insect cells revealed that SLC16A11 is a DIDS-sensitive transporter of sulfate (Vincourt JB, Jullien D, Amalric F, Girard JP. Molecular and functional characterization of SLC26A11, a sodium-independent sulfate transporter from high endothelial venules. FASEB J 17(8): 890-2, 2003). Tissue Distribution Evidence: Northern blot analysis showed the highest SLC26A11 transcript levels in placenta, kidney, and brain (Vincourt JB, Jullien D, Amalric F, Girard JP. Molecular and functional characterization of SLC26A11, a sodium-independent sulfate transporter from high endothelial venules. FASEB J 17(8): 890-2, 2003).
Tissues:Placenta, kidney, brain
Type:protein-coding
Sets:0
PharmGKB ID:PA37888
HPRD ID:11569
Substrates:Sulfate
Trivial Names:
Transcripts:NM_173626.3 [Chr.17(+): 78194200-78227308 GRCh37]
NM_001166347.1 [Chr.17(+): 78194200-78227308 GRCh37]
NM_001166348.1 [Chr.17(+): 78194200-78227308 GRCh37]
NM_001166349.1 [Chr.17(+): 78194200-78227308 GRCh37]
XM_005257243.1 [Chr.17(+): 78194211-78227301 GRCh37]
ENST00000361193 [Chr.17(+): 78194229-78227299 GRCh37]
ENST00000411502 [Chr.17(+): 78194237-78227297 GRCh37]
ENST00000546047 [Chr.17(+): 78194237-78227299 GRCh37]
ENST00000571072 [Chr.17(+): 78199381-78210809 GRCh37]
ENST00000571176 [Chr.17(+): 78195145-78201653 GRCh37]
ENST00000571215 [Chr.17(+): 78201651-78219044 GRCh37]
ENST00000571564 [Chr.17(+): 78194268-78210902 GRCh37]
ENST00000571602 [Chr.17(+): 78194246-78197054 GRCh37]
ENST00000571888 [Chr.17(+): 78194237-78219172 GRCh37]
ENST00000572226 [Chr.17(+): 78195099-78197106 GRCh37]
ENST00000572652 [Chr.17(+): 78194237-78196174 GRCh37]
ENST00000572725 [Chr.17(+): 78194268-78226515 GRCh37]
ENST00000573809 [Chr.17(+): 78194226-78197071 GRCh37]
ENST00000574967 [Chr.17(+): 78194237-78195592 GRCh37]
ENST00000575019 [Chr.17(+): 78222013-78226698 GRCh37]
ENST00000576126 [Chr.17(+): 78194237-78199715 GRCh37]
ENST00000577155 [Chr.17(+): 78193498-78197082 GRCh37]
Annotation History:View Events (12)

GTEx Expression by Gene and Transcript

The heat map summarizes relative expression by tissue type at two levels of tissue detail, e.g., 'Brain' and 'Brain - Amygdala'. Choose among four calculated expression values, including mean and median RPKM values, and quantile normalized (QN) distributions of these values. (Note that differences between some distributions are subtle.) The coloring is relative to the mean of all displayed values. All values are log base 2. (See also PMT GTEx Expression Plotting.) Click on a transcript or tissue to resort the data.

Tissues:
Expression values:
No expression data exists for SLC26A11.

Variant Data

View all PMT variants for SLC26A11 on UCSC Genome Browser
Showing SNP features for transcript:   
1000 Genomes  

20141104 phase 3 variant call set of the 20130502 sequence freeze and alignments for SNPs and short indels (indels > 255 and structural variants are not included here). This variant set contains 2504 individuals from 26 populations (mouse over population column heading for population sizes).
Showing gene variants in regions defined by NCBI RefSeq exons, putative promoter, and PMT resequencing assays.
Note: Frequencies are calculated directly from reported genotypes and may vary from consensus frequencies reported by the 1000 Genomes project, which relied on additional data and the GATK tool Variant Quality Score Recalibrator.
dbSNP build 142.
Array availability: I - found on Illumina Human1M-Duo BeadChip (2011-04-21)  A - found on Affymetrix Genome-Wide SNP Array 6.0 (2011-06-21)  
Download the SNP table data as a tab-delimited file.

Transmembrane prediction:

Non-synonymous amino acid changes shown in red, indels (insertions and deletions) in blue, and synonymous changes in green. Exon(s) indicated by black outlines.