| Common Name: | HMIT |
| HGNC Symbol: | SLC2A13 |
| HGNC Description: | solute carrier family 2 (facilitated glucose transporter), member 13 |
| HGNC ID: | 15956 |
| Chromosome: | Chr.12(-): 38435090-38785928 |
| Location: | 12q12 |
| OMIM: | 611036 |
| OMIM Phenotype: | None |
| Accessions: | AJ315644 |
| Nucleotide RefSeq: | NM_052885 |
| Protein RefSeq: | NP_443117 |
| Entrez: | 114134 |
| Isoforms: | 1 |
| Evidence: | Substrate In Vitro Evidence: Myo-inositol and related stereoisomers (Xenopus oocytes) Uldry,M., Ibberson,M., Horisberger,J.D., Chatton,J.Y., Riederer,B.M. and Thorens,B. Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain. EMBO J. 20 (16), 4467-4477 (2001). Tissue Distribution Evidence: A 4.5 kb HMIT transcript was expressed predominantly in the brain, with high expression found in cerebral cortex, hippocampus, hypothalamus, cerebellum and brainstem. HMIT was detected in RNA prepared from primary cultures of neuronal or glial cells. A low level of expression was detected in white, brown and epididymal adipose tissues, and in kidney. (Northern blotting) Uldry,M., Ibberson,M., Horisberger,J.D., Chatton,J.Y., Riederer,B.M. and Thorens,B. Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain. EMBO J. 20 (16), 4467-4477 (2001). |
| Tissues: | predominantly in the brain; low in white, brown and epididymal adipose tissues, and in kidney |
| Type: | protein coding |
| Sets: | 0 |
| PharmGKB ID: | PA38066 |
| HPRD ID: | 15363 |
| Substrates: | Myo-inositol and related stereoisomers |
| Trivial Names: | HMIT, MGC48624 |
| Transcripts: | NM_052885 [Chr.12(-): 38435090-38785928] |
View on UCSC Genome Browser or Ensembl Genome Browser
Transmembrane prediction:
Non-synonymous amino acid changes shown in red, indels (insertions and deletions) in blue, and synonymous changes in green. Exon(s) indicated by black outlines.