| Common Name: | GLUT3 |
| HGNC Symbol: | SLC2A3 |
| HGNC Description: | solute carrier family 2 (facilitated glucose transporter), member 3 |
| HGNC ID: | 11007 |
| Chromosome: | Chr.12(-): 7963094-7980138 |
| Location: | 12p13.3 |
| OMIM: | 138170 |
| OMIM Phenotype: | None |
| Accessions: | M20681 |
| Nucleotide RefSeq: | NM_006931 |
| Protein RefSeq: | NP_008862 |
| Entrez: | 6515 |
| Isoforms: | 1 |
| Evidence: | Substrate In Vitro Evidence: 2-deoxyglucose, D-galactose, D-glucose (Xenopus oocytes) Sarkar, H. K.; Thorens, B.; Lodish, H. F.; Kaback, H. R. Expression of the human erythrocyte glucose transporter in Escherichia coli. Proc. Nat. Acad. Sci. 85: 5463-5467, 1988 Substrate In Vivo Evidence: GLUT3 may play an important role in brain development. Vannucci RC, Vannucci SJ. Glucose metabolism in the developing brain. Semin Perinatol. 2000 Apr; 24(2): 107-15. Tissue Distribution Evidence: The first cDNA was cloned from human fetal skeletal muscle. The mRNA encoding this protein was present in most if not all tissues, although the amounts varied widely (abundant in the brain). (RNA blotting) Kayano, T.; Fukumoto, H.; Eddy, R. L.; Fan, Y.-S.; Byers, M. G.; Shows, T. B.; Bell, G. I. Evidence for a family of human glucose transporter-like proteins: sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues. J. Biol. Chem. 263: 15245-15248, 1988. |
| Tissues: | most tissues including skeletal muscle and |
| Type: | protein coding |
| Sets: | 0 |
| PharmGKB ID: | PA35877 |
| HPRD ID: | 00686 |
| Substrates: | 2-deoxyglucose, D-galactose, D-glucose |
| Trivial Names: | GLUT3, FLJ90380 |
| Transcripts: | NM_006931 [Chr.12(-): 7963094-7980138] |
View on UCSC Genome Browser or Ensembl Genome Browser
Transmembrane prediction:
Non-synonymous amino acid changes shown in red, indels (insertions and deletions) in blue, and synonymous changes in green. Exon(s) indicated by black outlines.