|HGNC Description:||solute carrier family 30 (zinc transporter), member 4|
|Chromosome:||Chr.15(-): 45774676-45815005 GRCh37|
|Evidence:||Substrate In Vitro Evidence: Zinc, expression of ZNT4 in a zinc-sensitive yeast cell line restored zinc resistance Huang et al 1997, Nature Genetics, Vol 17 (3), p. 292-97 Substrate In Vivo Evidence: A defect in ZNT4 is responsible for the lethal milk mouse. In this syndrome the mothers live, but the pups demonstrate zinc deficiency from feeding on the mother's milk and are unable to survive. Huang et al 1997, Nature Genetics, Vol 17 (3), p. 292-97 Tissue Distribution Evidence: Ubiquitous distribution by Northern analysis in rats Liuzzi et al 2001, Journal of Nutrition, Vol 131, p.46-52|
|Tissues:||widespread, secretory glands (by mRNA analysis in rodents)|
|Transcripts:||NM_013309.4 [Chr.15(-): 45774676-45815002 GRCh37]|
XM_005254656.1 [Chr.15(-): 45774676-45815005 GRCh37]
|ENST00000261867 [Chr.15(-): 45771809-45815005 GRCh37]|
ENST00000559667 [Chr.15(-): 45795029-45814434 GRCh37]
|Annotation History:||View Events (10)|
GTEx Expression by Gene and Transcript
The heat map summarizes relative expression by tissue type at two levels of tissue detail, e.g., 'Brain' and 'Brain - Amygdala'. Choose among four calculated expression values, including mean and median RPKM values, and quantile normalized (QN) distributions of these values. (Note that differences between some distributions are subtle.) The coloring is relative to the mean of all displayed values. All values are log base 2. (See also PMT GTEx Expression Plotting.) Click on a transcript or tissue to resort the data.
Showing gene variants in regions defined by NCBI RefSeq exons, putative promoter, and PMT resequencing assays.
Note: Frequencies are calculated directly from reported genotypes and may vary from consensus frequencies reported by the 1000 Genomes project, which relied on additional data and the GATK tool Variant Quality Score Recalibrator.
Non-synonymous amino acid changes shown in red, indels (insertions and deletions) in blue, and synonymous changes in green. Exon(s) indicated by black outlines.