|HGNC Description:||solute carrier family 31 (copper transporter), member 2|
|Chromosome:||Chr.9(+): 115913238-115926422 GRCh37|
|Evidence:||Substrate In Vitro Evidence: It has not been conclusively shown that hCTR2 transports copper. It was identified by homology to hCTR1 and a yeast copper transporter (yCTR2). It has been speculated that hCTR2 is likely to be an intracellular copper transporter because the yeast ortholog was localized to the vacuole. Zhou and Gitschier 1997, PNAS, Vol 94, p.7481-86 Portney et al 2001, Mol Genet Genome, Vol 265, p.873-882 Petris 2003, Pflugers Arch Tissue Distribution Evidence: Present in all tissues tested by Northern Blot, highest expression in placenta Zhou and Gitschier 1997, PNAS, Vol 94, p.7481-86|
|Trivial Names:||CTR2, COPT2, hCTR2|
|Transcripts:||NM_001860.2 [Chr.9(+): 115913238-115926422 GRCh37]||ENST00000259392 [Chr.9(+): 115913222-115926417 GRCh37]|
ENST00000374220 [Chr.9(+): 115913310-115926417 GRCh37]
ENST00000490809 [Chr.9(+): 115913256-115914596 GRCh37]
|Annotation History:||View Events (2)|
GTEx Expression by Gene and Transcript
The heat map summarizes relative expression by tissue type at two levels of tissue detail, e.g., 'Brain' and 'Brain - Amygdala'. Choose among four calculated expression values, including mean and median RPKM values, and quantile normalized (QN) distributions of these values. (Note that differences between some distributions are subtle.) The coloring is relative to the mean of all displayed values. All values are log base 2. (See also PMT GTEx Expression Plotting.) Click on a transcript or tissue to resort the data.
Showing gene variants in regions defined by NCBI RefSeq exons, putative promoter, and PMT resequencing assays.
Note: Frequencies are calculated directly from reported genotypes and may vary from consensus frequencies reported by the 1000 Genomes project, which relied on additional data and the GATK tool Variant Quality Score Recalibrator.
Transmembrane prediction: TOPO2 image is not available.