UCSF Pharmacogenetics of Membrane Transporters
Gene View
Common Name:MgtE
HGNC Symbol:SLC41A1
HGNC Description:solute carrier family 41 (magnesium transporter), member 1
HGNC ID:19429
Superfamily:SLC
Chromosome:Chr.1(-): 205758221-205782887 GRCh37
Location:1q32.1
OMIM:610801
OMIM Phenotype:None
Accessions:AJ514402,AK092123,AK093254,AK125075,AK128069,AL831
Nucleotide RefSeq:NM_173854
Protein RefSeq:NP_776253
Entrez:254428
Ensembl:ENSG00000133065
Isoforms:2
Evidence:Substrate In Vitro Evidence: 1. Possibly Magnesium - Wabakken T et al, Biochemical and Biophysical Research Communications 2003: 718-724 Tissue Distribution Evidence: 1. High in Heart, Testis, Lower in skeletal muscle, prostate, Adrenal gland, thyroid - Northern - Wabakken T et al, Biochemical and Biophysical Research Communications 2003: 718-724
Tissues:heat, testis > skeletal muscle, prostate, adrenal gland, thyroid
Type:protein-coding
Sets:0
PharmGKB ID:PA134889327
HPRD ID:15388
Substrates:possibly magnesium
Trivial Names:MgtE
Transcripts:NM_173854.4 [Chr.1(-): 205758221-205782161 GRCh37]
XM_005245069.1 [Chr.1(-): 205758221-205782887 GRCh37]
ENST00000367137 [Chr.1(-): 205758221-205782304 GRCh37]
ENST00000468057 [Chr.1(-): 205758222-205770616 GRCh37]
ENST00000484000 [Chr.1(-): 205779427-205782876 GRCh37]
ENST00000484228 [Chr.1(-): 205760048-205765744 GRCh37]
Annotation History:View Events (11)

GTEx Expression by Gene and Transcript

The heat map summarizes relative expression by tissue type at two levels of tissue detail, e.g., 'Brain' and 'Brain - Amygdala'. Choose among four calculated expression values, including mean and median RPKM values, and quantile normalized (QN) distributions of these values. (Note that differences between some distributions are subtle.) The coloring is relative to the mean of all displayed values. All values are log base 2. (See also PMT GTEx Expression Plotting.) Click on a transcript or tissue to resort the data.

Tissues:
Expression values:
No expression data exists for SLC41A1.

Variant Data

View all PMT variants for SLC41A1 on UCSC Genome Browser
Showing SNP features for transcript:   
1000 Genomes  

20141104 phase 3 variant call set of the 20130502 sequence freeze and alignments for SNPs and short indels (indels > 255 and structural variants are not included here). This variant set contains 2504 individuals from 26 populations (mouse over population column heading for population sizes).
Showing gene variants in regions defined by NCBI RefSeq exons, putative promoter, and PMT resequencing assays.
Note: Frequencies are calculated directly from reported genotypes and may vary from consensus frequencies reported by the 1000 Genomes project, which relied on additional data and the GATK tool Variant Quality Score Recalibrator.
dbSNP build 142.
Array availability: I - found on Illumina Human1M-Duo BeadChip (2011-04-21)  A - found on Affymetrix Genome-Wide SNP Array 6.0 (2011-06-21)  
Download the SNP table data as a tab-delimited file.

Transmembrane prediction: TOPO2 image is not available.