UCSF Pharmacogenetics of Membrane Transporters
Gene View
Common Name:SLCO2A1
HGNC Symbol:SLCO2A1
HGNC Description:solute carrier organic anion transporter family, member 2A1
HGNC ID:10955
Superfamily:SLC
Chromosome:Chr.3(-): 133651540-133748920 GRCh37
Location:3q21
OMIM:601460
OMIM Phenotype:None
Accessions:NM_005630
Nucleotide RefSeq:NM_005630
Protein RefSeq:NP_005621
Entrez:6578
Ensembl:ENSG00000174640
Isoforms:1
Evidence:Substrate In Vitro Evidence: prostaglandins: HeLa cells [1] PGE1 PGE2 PGD2 PGF2 thromboxane B2 (TXB2) HeLa cells [1] Tissue Distribution Evidence: Ubiquitously expressed highest in: heart, skeletal muscle and pancreas Northern [1] 1. Lu, R., et al., Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA(hPGT). J Clin Invest, 1996. 98(5): p. 1142-9.
Tissues:Ubiquitously expressed
Type:protein-coding
Sets:V
PharmGKB ID:PA35840
HPRD ID:03269
Substrates:PGE1, PGE2, PGD2, PGF2, thromboxane B2
Trivial Names:PGT, MATR1, PHOAR2, OATP2A1, SLC21A2
Transcripts:NM_005630.2 [Chr.3(-): 133651540-133748920 GRCh37]
ENST00000310926 [Chr.3(-): 133651540-133748920 GRCh37]
ENST00000462770 [Chr.3(-): 133661156-133748769 GRCh37]
ENST00000464676 [Chr.3(-): 133669796-133748769 GRCh37]
ENST00000477061 [Chr.3(-): 133667498-133668060 GRCh37]
ENST00000478651 [Chr.3(-): 133674187-133748769 GRCh37]
ENST00000478662 [Chr.3(-): 133698391-133771028 GRCh37]
ENST00000481359 [Chr.3(-): 133653483-133748767 GRCh37]
ENST00000493729 [Chr.3(-): 133653455-133748758 GRCh37]

GTEx Expression by Gene and Transcript

The heat map summarizes relative expression by tissue type at two levels of tissue detail, e.g., 'Brain' and 'Brain - Amygdala'. Choose among four calculated expression values, including mean and median RPKM values, and quantile normalized (QN) distributions of these values. (Note that differences between some distributions are subtle.) The coloring is relative to the mean of all displayed values. All values are log base 2. (See also PMT GTEx Expression Plotting.) Click on a transcript or tissue to resort the data.

Tissues:
Expression values:
No expression data exists for SLCO2A1.

Variant Data

View all PMT variants for SLCO2A1 on UCSC Genome Browser
Showing SNP features for transcript: NM_005630  
1000 Genomes  

20141104 phase 3 variant call set of the 20130502 sequence freeze and alignments for SNPs and short indels (indels > 255 and structural variants are not included here). This variant set contains 2504 individuals from 26 populations (mouse over population column heading for population sizes).
Showing gene variants in regions defined by NCBI RefSeq exons, putative promoter, and PMT resequencing assays.
Note: Frequencies are calculated directly from reported genotypes and may vary from consensus frequencies reported by the 1000 Genomes project, which relied on additional data and the GATK tool Variant Quality Score Recalibrator.
dbSNP build 142.
Array availability: I - found on Illumina Human1M-Duo BeadChip (2011-04-21)  A - found on Affymetrix Genome-Wide SNP Array 6.0 (2011-06-21)  
Download the SNP table data as a tab-delimited file.

Transmembrane prediction:

Non-synonymous amino acid changes shown in red, indels (insertions and deletions) in blue, and synonymous changes in green. Exon(s) indicated by black outlines.