UCSF Pharmacogenetics of Membrane Transporters
Snp Publications
PMT SNP UID:2865
  1. Ray A, Tennakoon L, Keller J, Sarginson JE, Ryan HS, Murphy GM, Lazzeroni LC, Trivedi MH, Kocsis JH, DeBattista C, Schatzberg AF. ABCB1 (MDR1) predicts remission on P-gp substrates in chronic depression. Pharmacogenomics J. 2014 Dec 9. PMID: 25487678.
  2. Sadhasivam S, Chidambaran V, Zhang X, Meller J, Esslinger H, Zhang K, Martin LJ, McAuliffe J. Opioid-induced respiratory depression: ABCB1 transporter pharmacogenetics. Pharmacogenomics J. 2014 Oct 14. PMID: 25311385.
  3. Baskin Y, Amirfallah A, Calibasi G, Olgun N. Hepatopathy-Thrombocytopenia Syndrome During Actinomycin D Treatment May Be Related to MDR1 (ABCB1) Gene Polymorphisms. Am J Ther. 2014 Jan 9. PMID: 24413370.
  4. Skoglund K, Moreno SB, Baytar M, Jönsson JI, Gréen H. ABCB1 haplotypes do not influence transport or efficacy of tyrosine kinase inhibitors in vitro. Pharmgenomics Pers Med. 2013 Aug 20;663-72. PMID: 24019750.
  5. Dogruer D, Tug E, Bes C, Soy M. Lack of an effect of CYP3A4 and MDR1 gene polymorphisms on colchicine pharmacogenetics in the treatment of Familial Mediterranean fever. Genet Mol Res. 2013 Jan 24;12(AOP). PMID: 23408444.
  6. Barratt DT, Coller JK, Hallinan R, Byrne A, White JM, Foster DJ, Somogyi AA. ABCB1 haplotype and OPRM1 118A > G genotype interaction in methadone maintenance treatment pharmacogenetics. Pharmgenomics Pers Med. 2012;553-62. PMID: 23226062.
  7. Swart M, Ren Y, Smith P, Dandara C. ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS Patients. Front Genet. 2012;3236. PMID: 23133441.
  8. Jordán de Luna C, Herrero Cervera MJ, Sánchez Lázaro I, Almenar Bonet L, Poveda Andrés JL, Aliño Pellicer SF. Pharmacogenetic Study of ABCB1 and CYP3A5 Genes During the First Year Following Heart Transplantation Regarding Tacrolimus or Cyclosporine Levels. Transplant Proc. 2011 Jul-Aug;43(6):2241-3. PMID: 21839244.
  9. Sainz J, Rudolph A, Hein R, Hoffmeister M, Buch S, von Schönfels W, Hampe J, Schafmayer C, Völzke H, Frank B, Brenner H, Försti A, Hemminki K, Chang-Claude J. Association of genetic polymorphisms in ESR2, HSD17B1, ABCB1, and SHBG genes with colorectal cancer risk. Endocr Relat Cancer. 2011;18(2):265-276. PMID: 21317201.
  10. Fajac A, Gligorov J, Rezai K, Lévy P, Lévy E, Selle F, Beerblock K, Avenin D, Saintigny P, Hugonin S, Bernaudin JF, Lokiec F. Effect of ABCB1 C3435T polymorphism on docetaxel pharmacokinetics according to menopausal status in breast cancer patients. Br J Cancer. 2010 Jul 13. PMID: 20628376.
  11. Jeannesson E, Siest G, Bastien B, Albertini L, Aslanidis C, Schmitz G, Visvikis-Siest S. Association of ABCB1 gene polymorphisms with plasma lipid and apolipoprotein concentrations in the Stanislas Cohort. Clin Chim Acta. 2009 Mar 10. PMID: 19285054.
  12. Gex-Fabry M, Eap CB, Oneda B, Gervasoni N, Aubry JM, Bondolfi G, Bertschy G. CYP2D6 and ABCB1 genetic variability: influence on paroxetine plasma level and therapeutic response. Ther Drug Monit. 2008 Aug;30(4):474-82. PMID: 18641553.
  13. Gow JM, Hodges LM, Chinn LW, Kroetz DL. Substrate-dependent effects of human ABCB1 coding polymorphisms. J Pharmacol Exp Ther. 2008 May;325(2):435-42. PMID: 18287207.
  14. Crettol S, Venetz JP, Fontana M, Aubert JD, Ansermot N, Fathi M, Pascual M, Eap CB. Influence of ABCB1 genetic polymorphisms on cyclosporine intracellular concentration in transplant recipients. Pharmacogenet Genomics. 2008 Apr;18(4):307-15. PMID: 18334915.
  15. Jeannesson E, Albertini L, Siest G, Gomes AM, Ribeiro V, Aslanidis C, Schmitz G, Visvikis-Siest S. Determination of ABCB1 polymorphisms and haplotypes frequencies in a French population. Fundam Clin Pharmacol. 2007 Aug;21(4):411-8. PMID: 17635180.
  16. Brant SR, Panhuysen CI, Nicolae D, Reddy DM, Bonen DK, Karaliukas R, Zhang L, Swanson E, Datta LW, Moran T, Ravenhill G, Duerr RH, Achkar JP, Karban AS, Cho JH. MDR1 Ala893 polymorphism is associated with inflammatory bowel disease. Am J Hum Genet. 2003 Dec;73(6):1282-92. PMID: 14610718.
  17. Kimchi-Sarfaty C, Gribar JJ, Gottesman MM. Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system. Mol Pharmacol. 2002 Jul;62(1):1-6. PMID: 12065748.
  18. Cascorbi I, Gerloff T, Johne A, Meisel C, Hoffmeyer S, Schwab M, Schaeffeler E, Eichelbaum M, Brinkmann U, Roots I. Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther. 2001 Mar;69(3):169-74. PMID: 11240981.
  19. Declèves X, Chevillard S, Charpentier C, Vielh P, Laplanche JL. A new polymorphism (N21D) in the exon 2 of the human MDR1 gene encoding the P-glycoprotein. Hum Mutat. 2000 May;15(5):486. PMID: 10790226.