UCSF Pharmacogenetics of Membrane Transporters
Snp Publications
  1. Takayoshi K, Sagara K, Uchino K, Kusaba H, Sakamoto N, Iguchi A, Baba E. A case of metastatic renal cell carcinoma and bile duct carcinoma treated with a combination of sunitinib and gemcitabine. BMC Cancer. 2015 May 22;15(1):426. PMID: 26001650.
  2. Wang YX, Li JL, Wang XD, Zhang Y, Wang CX, Huang M. Diltiazem augments the influence of MDR1 genotype status on cyclosporine concentration in Chinese patients with renal transplantation. Acta Pharmacol Sin. 2015 Apr 20. PMID: 25891084.
  3. Wolking S, Schaeffeler E, Lerche H, Schwab M, Nies AT. Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature. Clin Pharmacokinet. 2015 Apr 10. PMID: 25860377.
  4. Breitenstein B, Brückl TM, Ising M, Müller-Myhsok B, Holsboer F, Czamara D. ABCB1 gene variants and antidepressant treatment outcome: A meta-analysis. Am J Med Genet B Neuropsychiatr Genet. 2015 Apr 2. PMID: 25847751.
  5. Kim MG, Kim IW, Choi B, Han N, Yun HY, Park S, Oh JM. Population Pharmacokinetics of Cyclosporine in Hematopoietic Stem Cell Transplant Patients: Consideration of Genetic Polymorphisms. Ann Pharmacother. 2015 Mar 27. PMID: 25818517.
  6. Lambrechts S, Lambrechts D, Despierre E, Van Nieuwenhuysen E, Smeets D, Debruyne PR, Renard V, Vroman P, Luyten D, Neven P, Amant F, Leunen K, Vergote I, Belgian and Luxembourg Gynaecological Oncology Group (BGOG). Genetic variability in drug transport, metabolism or DNA repair affecting toxicity of chemotherapy in ovarian cancer. BMC Pharmacol Toxicol. 2015 Feb 27;16(1):2. PMID: 25881102.
  7. He H, Yin J, Li X, Zhang Y, Xu X, Zhai M, Chen J, Qian C, Zhou H, Liu Z. Association of ABCB1 polymorphisms with prognostic outcomes of anthracycline and cytarabine in Chinese patients with acute myeloid leukemia. Eur J Clin Pharmacol. 2015 Jan 9. PMID: 25567217.
  8. Robertsen I, Vethe NT, Midtvedt K, Falck P, Christensen H, Åsberg A. Closer to the site of action; everolimus concentrations in peripheral blood mononuclear cells correlate well with whole blood concentrations. Ther Drug Monit. 2015 Jan 6. PMID: 25565673.
  9. Megías-Vericat JE, Rojas L, Herrero MJ, Bosó V, Montesinos P, Moscardó F, Poveda JL, Sanz MÁ, Aliño SF. Influence of ABCB1 polymorphisms upon the effectiveness of standard treatment for acute myeloid leukemia: A systematic review and meta-analysis of observational studies. Pharmacogenomics J. 2015 Jan 6. PMID: 25558979.
  10. Pongstaporn W, Pakakasama S, Chaksangchaichote P, Pongtheerat T, Hongeng S, Permitr S. MDR1 C3435T and C1236T Polymorphisms: Association with High-risk Childhood Acute Lymphoblastic Leukemia. Asian Pac J Cancer Prev. 2015;16(7):2839-43. PMID: 25854371.
  11. Li H, Wang B, Chang C, Wu M, Xu Y, Jiang Y. The Roles of Variants in Human Multidrug Resistance (MDR1) Gene and Their Haplotypes on Antiepileptic Drugs Response: A Meta-Analysis of 57 Studies. PLoS One. 2015;10(3):e0122043. PMID: 25816099.
  12. Zhou Z, Chen Q, Zuo D, Wang H, Hua Y, Cai Z. ABCB1 (rs1128503) polymorphism and response to chemotherapy in patients with malignant tumors-evidences from a meta-analysis. Int J Clin Exp Med. 2015;8(1):265-72. PMID: 25784996.
  13. Cao Y, Qu C, Chen Y, Li L, Wang X. Association of abcb1 polymorphisms and ulcerative colitis susceptibility. Int J Clin Exp Pathol. 2015;8(1):943-7. PMID: 25755800.
  14. Saidijam M, Mahjub H, Shabab N, Yadegarazari R. Simultaneous Analysis of Multidrug Resistance 1(MDR1) C3435T, G2677T/A, and C1236T Genotypes in Hamadan City Population, West of Iran. Iran Biomed J. 2015 Jan;19(1):57-62. PMID: 25605491.
  15. Ma L, Liu H, Ruan L, Yang X, Yang H, Feng Y. Multidrug resistance gene 1 C1236T polymorphism and susceptibility to leukemia: A meta-analysis. Biomed Rep. 2015 Jan;3(1):83-87. PMID: 25469253.
  16. Choi JR, Kim JO, Kang DR, Shin JY, Zhang XH, Oh JE, Park JY, Kim KA, Kang JH. Genetic Variations of Drug Transporters Can Influence on Drug Response in Patients Treated with Docetaxel Chemotherapy. Cancer Res Treat. 2014 Dec 16. PMID: 25648089.
  17. Peñas-Lledó E, Guillaume S, Delgado A, Naranjo ME, Jaussent I, LLerena A, Courtet P. ABCB1 gene polymorphisms and violent suicide attempt among survivors. J Psychiatr Res. 2014 Dec 15. PMID: 25543520.
  18. Kobayashi H, Sato K, Niioka T, Miura H, Ito H, Miura M. Relationship Among Gefitinib Exposure, Polymorphisms of Its Metabolizing Enzymes and Transporters, and Side Effects in Japanese Patients With Non-Small-Cell Lung Cancer. Clin Lung Cancer. 2014 Dec 11. PMID: 25554506.
  19. Koo DH, Ryu MH, Ryoo BY, Beck MY, Na YS, Shin JG, Lee SS, Kim EY, Kang YK. Association of ABCG2 polymorphism with clinical efficacy of imatinib in patients with gastrointestinal stromal tumor. Cancer Chemother Pharmacol. 2014 Nov 23. PMID: 25417047.
  20. Ali MA, Elsalakawy WA. ABCB1 haplotypes but not individual SNPs predict for optimal response/failure in Egyptian patients with chronic-phase chronic myeloid leukemia receiving imatinib mesylate. Med Oncol. 2014 Nov;31(11):279. PMID: 25301112.
  21. Yang QF, Chen BL, Zhang QS, Zhu ZH, Hu B, He Y, Gao X, Wang YM, Hu PJ, Chen MH, Zeng ZR. Contribution of MDR1 gene polymorphisms on IBD predisposition and response to glucocorticoids in IBD in Chinese population. J Dig Dis. 2014 Oct 27. PMID: 25346426.
  22. Mei Y, Wang SY, Li Y, Yi SQ, Wang CY, Yang M, Duan KM. The role of SLCO1B1, ABCB1 and CHRNA1 gene polymorphisms on the efficacy of rocuronium in Chinese patients. J Clin Pharmacol. 2014 Oct 3. PMID: 25279974.
  23. Fehér A, Juhász A, Pákáski M, Kálmán J, Janka Z. ABCB1 C3435T Polymorphism Influences the Risk for Alzheimer's Disease. J Mol Neurosci. 2014 Oct 2. PMID: 25273678.
  24. Zheng Q, Wu H, Yu Q, Kim DH, Lipton JH, Angelini S, Soverini S, Vivona D, Takahashi N, Cao J. ABCB1 polymorphisms predict imatinib response in chronic myeloid leukemia patients: a systematic review and meta-analysis. Pharmacogenomics J. 2014 Sep 23. PMID: 25245580.
  25. Martinelli M, Scapoli L, Cura F, Rodia MT, Ugolini G, Montroni I, Solmi R. Colorectal cancer susceptibility: apparent gender-related modulation by ABCB1 gene polymorphisms. J Biomed Sci. 2014 Sep 4;21(1):89. PMID: 25355168.
  26. Saracino A, Muscaridola N, Cifarelli RA, Stallone G, Grandaliano G, Santarsia G. Multidrug-resistance 1 gene single-nucleotide polymorphisms do not influence long-term graft survival after kidney transplantation. Transplant Proc. 2014 Sep;46(7):2214-9. PMID: 25242754.
  27. Weissfeld JL, Diergaarde B, Nukui T, Buch S, Pennathur A, Socinski MA, Siegfried JM, Romkes M. Inherited Variation in the ATP-Binding Cassette Transporter ABCB1 and Survival after Chemotherapy for Stage III-IV Lung Cancer. J Thorac Oncol. 2014 Sep;9(9):1264-71. PMID: 25122423.
  28. DiDomenico RJ, Bress AP, Na-Thalang K, Tsao YY, Groo VL, Deyo KL, Patel SR, Bishop JR, Bauman JL. Use of a Simplified Nomogram to Individualize Digoxin Dosing versus Standard Dosing Practices in Patients with Heart Failure. Pharmacotherapy. 2014 Aug 28. PMID: 25164709.
  29. Jakobsen Falk I, Fyrberg A, Paul E, Nahi H, Hermanson M, Rosenquist R, Höglund M, Palmqvist L, Stockelberg D, Wei Y, Gréen H, Lotfi K. Impact of ABCB1 single nucleotide polymorphisms 1236C>T and 2677G>T on overall survival in FLT3 wild-type de novo AML patients with normal karyotype. Br J Haematol. 2014 Aug 23. PMID: 25155901.
  30. Kim KA, Cha YJ, Lee HM, Joo HJ, Park JY. Effects of the ABCG2 and ABCB1 drug transporter polymorphisms on the pharmacokinetics of bicalutamide in humans. Clin Chim Acta. 2014 Aug 11. PMID: 25124867.
  31. Yaya K, Hind D, Meryem Q, Asma Q, Said B, Sellama N. Single nucleotide polymorphisms of multidrug resistance gene 1 (MDR1) and risk of chronic myeloid leukemia. Tumour Biol. 2014 Aug 5. PMID: 25087925.
  32. Zgheib NK, Akra-Ismail M, Aridi C, Mahfouz R, Abboud MR, Solh H, Muwakkit SA. Genetic polymorphisms in candidate genes predict increased toxicity with methotrexate therapy in Lebanese children with acute lymphoblastic leukemia. Pharmacogenet Genomics. 2014 Aug;24(8):387-96. PMID: 25007187.
  33. Dizdarevic S, Aplin M, Newport MJ, Ryan N, Holt S, Goubet S, Goldberg L, Miles KA, Peters AM. Old tracer for a new purpose: potential role for 99mTc-2-methoxyisobutylisonitrile (99mTc-MIBI) in renal transplant care. Nucl Med Commun. 2014 Jul 14. PMID: 25025147.
  34. Liu S, Yi Z, Ling M, Shi J, Qiu Y, Yang S. Predictive potential of ABCB1, ABCC3, and GSTP1 gene polymorphisms on osteosarcoma survival after chemotherapy. Tumour Biol. 2014 Jul 5. PMID: 24996541.
  35. Cortejoso L, García MI, García-Alfonso P, Grávalos C, Robles L, González-Haba E, Sanjurjo M, López-Fernández LA. [Validation of genetic polymorphisms associated to the toxicity of chemotherapy in colorectal cancer patients]. Farm Hosp. 2014 Jul 1;38(4):283-90. PMID: 25137161.
  36. Takakuwa O, Oguri T, Uemura T, Kunii E, Nakao M, Hijikata H, Kawaguchi Y, Ohkubo H, Takemura M, Maeno K, Niimi A. ABCB1 Polymorphism as a Predictive Biomarker for Amrubicin-induced Neutropenia. Anticancer Res. 2014 Jul;34(7):3517-22. PMID: 24982363.
  37. Vasilopoulos Y, Sarri C, Zafiriou E, Patsatsi A, Stamatis C, Ntoumou E, Fassos I, Tsalta A, Karra A, Roussaki-Schulze A, Sotiriadis D, Mamuris Z, Sarafidou T. A pharmacogenetic study of ABCB1 polymorphisms and cyclosporine treatment response in patients with psoriasis in the Greek population. Pharmacogenomics J. 2014 Jun 3. PMID: 24889923.
  38. Beuselinck B, Lambrechts D, Van Brussel T, Wolter P, Cardinaels N, Joniau S, Lerut E, Karadimou A, Couchy G, Sebe P, Ravaud A, Zerbib M, Caty A, Paridaens R, Schöffski P, Verkarre V, Berger J, Patard JJ, Zucman-Rossi J, Oudard S. Efflux pump ABCB1 single nucleotide polymorphisms and dose reductions in patients with metastatic renal cell carcinoma treated with sunitinib. Acta Oncol. 2014 May 301-10. PMID: 24874929.
  39. Rustemoglu A, Gumus-Akay G, Karakus N, Yigit S, Sahin S, Tasliyurt T. Association analysis of three ABCB1 (MDR1) gene variants (C1236T, G2677A/T and C3435T) and their genotype/haplotype combinations with the familial Mediterranean fever. Xenobiotica. 2014 Apr 28. PMID: 24773260.
  40. Tulsyan S, Chaturvedi P, Singh AK, Agarwal G, Lal P, Agrawal S, Mittal RD, Mittal B. Assessment of clinical outcomes in breast cancer patients treated with taxanes: multi-analytical approach. Gene. 2014 Apr 2. PMID: 24704000.
  41. Nahar R, Saxena R, Deb R, Parakh R, Shad S, Sethi PK, Takkar P, Verma IC. CYP2C9, VKORC1, CYP4F2, ABCB1 and F5 variants: Influence on quality of long-term anticoagulation. Pharmacol Rep. 2014 Apr;66(2):243-9. PMID: 24911077.
  42. Zu B, Li Y, Wang X, He D, Huang Z, Feng W. MDR1 gene polymorphisms and imatinib response in chronic myeloid leukemia: a meta-analysis. Pharmacogenomics. 2014 Apr;15(5):667-77. PMID: 24798723.
  43. Vivona D, Lima LT, Rodrigues AC, Bueno CT, Alcantara GK, Barros LS, DE Moraes Hungria VT, Chiattone CS, DE Lourdes Lopes Ferrari Chauffaille M, Guerra-Shinohara EM. ABCB1 haplotypes are associated with P-gp activity and affect a major molecular response in chronic myeloid leukemia patients treated with a standard dose of imatinib. Oncol Lett. 2014 Apr;7(4):1313-1319. PMID: 24660038.
  44. Schoeppler KE, Aquilante CL, Kiser TH, Fish DN, Zamora MR. The impact of genetic polymorphisms, diltiazem, and demographic variables on everolimus trough concentrations in lung transplant recipients. Clin Transplant. 2014 Mar 13. PMID: 24628014.
  45. Ferrari M, Guasti L, Maresca A, Mirabile M, Contini S, Grandi AM, Marino F, Cosentino M. Association between statin-induced creatine kinase elevation and genetic polymorphisms in SLCO1B1, ABCB1 and ABCG2. Eur J Clin Pharmacol. 2014 Mar 6. PMID: 24595600.
  46. Cusinato DA, Lacchini R, Romao EA, Moysés-Neto M, Coelho EB. Relationship of Cyp3a5 Genotype and Abcb1 Diplotype to Tacrolimus Disposition in Brazilian Kidney Transplant Patients. Br J Clin Pharmacol. 2014 Feb 17. PMID: 24528196.
  47. Xuan M, Li H, Fu R, Yang Y, Zhang D, Zhang X, Yang R. Association of ABCB1 gene polymorphisms and haplotypes with therapeutic efficacy of glucocorticoids in Chinese patients with immune thrombocytopenia. Hum Immunol. 2014 Jan 29. PMID: 24486577.
  48. Alzoubi KH, Khabour OF, Al-Azzam SI, Mayyas F, Mhaidat NM. The role of Multidrug Resistance-1 (MDR1) variants in response to atorvastatin among Jordanians. Cytotechnology. 2014 Jan 11. PMID: 24414406.
  49. Baskin Y, Amirfallah A, Calibasi G, Olgun N. Hepatopathy-Thrombocytopenia Syndrome During Actinomycin D Treatment May Be Related to MDR1 (ABCB1) Gene Polymorphisms. Am J Ther. 2014 Jan 9. PMID: 24413370.
  50. Xue Y, Zhao ZQ, Hong D, Zhang HJ, Chen HX, Fan SW. MDR1 Gene Polymorphisms Are Associated with Glucocorticoid-Induced Avascular Necrosis of the Femoral Head in a Chinese Population. Genet Test Mol Biomarkers. 2014 Jan 4. PMID: 24387690.
  51. Naumovska Z, Nestorovska AK, Sterjev Z, Filipce A, Dimovski A, Suturkova Lj. Genotype variability and haplotype profile of ABCB1 (MDR1) gene polymorphisms in macedonian population. Prilozi. 2014;35(3):121-34. PMID: 25725700.
  52. Hamzah S, Teh LK, Siew JS, Ahmad G, Wong HS, Zakaria ZA, Salleh MZ. Pharmacogenotyping of CYP3A5 in predicting dose-adjusted trough levels of tacrolimus among Malaysian kidney-transplant patients. Can J Physiol Pharmacol. 2014 Jan;92(1):50-7. PMID: 24383873.
  53. Pramanik S, Surendran ST, Devi S, Krishnamurthi K, Chakrabarti T. Frequency and genotype distribution of ABCB1 gene polymorphisms among Maharashtrian population of Central India. Xenobiotica. 2013 Dec 6. PMID: 24308438.
  54. Lee J, Huang H, Chen Y, Lu X. ABCB1 haplotype influences the sirolimus dose requirements in Chinese renal transplant recipients. Biopharm Drug Dispos. 2013 Nov 27. PMID: 24285256.
  55. Kim KA, Joo HJ, Lee HM, Park JY. Influence of ABCB1 and CYP3A5 genetic polymorphisms on the pharmacokinetics of quetiapine in healthy volunteers. Pharmacogenet Genomics. 2013 Nov 14. PMID: 24240480.
  56. Santos M, Carvalho S, Lima L, Nogueira A, Assis J, Mota-Pereira J, Pimentel P, Maia D, Correia D, Gomes S, Cruz A, Medeiros R. Common Genetic Polymorphisms in the ABCB1 Gene Are Associated with Risk of Major Depressive Disorder in Male Portuguese Individuals. Genet Test Mol Biomarkers. 2013 Nov 7. PMID: 24200053.
  57. Ferraresso M, Belingheri M, Turolo S, Ghio L, Tirelli AS, Grillo P, Lepore M, Edefonti A. Long-term effects of ABCB1 and SXR SNPs on the systemic exposure to cyclosporine in pediatric kidney transplant patients. Pharmacogenomics. 2013 Oct;14(13):1605-1613. PMID: 24088131.
  58. Alzoubi KH, Khabour OF, Al-Azzam SI, Mayyas F. The role of multidrug resistance-1 (MDR1) variants in response to fexofenadine among Jordanians. Int J Clin Pharmacol Ther. 2013 Sep 17. PMID: 24040855.
  59. Brambila-Tapia AJ. MDR1 (ABCB1) polymorphisms: functional effects and clinical implications. Rev Invest Clin. 2013 Sep-Oct;65(5):445-54. PMID: 24687344.
  60. Youssef DM, Attia TA, El-Shal AS, Abduelometty FA. Multi-drug resistance-1 gene polymorphisms in nephrotic syndrome: Impact on susceptibility and response to steroids. Gene. 2013 Aug 27. PMID: 23994685.
  61. Skoglund K, Moreno SB, Baytar M, Jönsson JI, Gréen H. ABCB1 haplotypes do not influence transport or efficacy of tyrosine kinase inhibitors in vitro. Pharmgenomics Pers Med. 2013 Aug 20;663-72. PMID: 24019750.
  62. Kassogue Y, Dehbi H, Nassereddine S, Quachouh M, Nadifi S. Genotype Variability and Haplotype Frequency of MDR1 (ABCB1) Gene Polymorphism in Morocco. DNA Cell Biol. 2013 Aug 9. PMID: 23930592.
  63. Johnatty SE, Beesley J, Gao B, Chen X, Lu Y, Law MH, Henderson MJ, Russell AJ, Hedditch EL, Emmanuel C, Fereday S, Webb PM, Australian Ovarian Cancer Study Group, Goode EL, Vierkant RA, Fridley BL, Cunningham JM, Fasching PA, Beckmann MW, Ekici AB, Hogdall E, Kjaer SK, Jensen A, Hogdall C, Brown R, Paul J, Lambrechts S, Despierre E, Vergote I, Lester J, Karlan BY, Heitz F, du Bois A, Harter P, Schwaab I, Bean Y, Pejovic T, Levine DA, Goodman MT, Camey ME, Thompson PJ, Lurie G, Shildkraut J, Berchuck A, Terry KL, Cramer DW, Norris MD, Haber M, Macgregor S, Defazio A, Chenevix-Trench G. ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: A comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas. Gynecol Oncol. 2013 Jul 31. PMID: 23917080.
  64. Gómez-Bravo MA, Salcedo M, Fondevila C, Suarez F, Castellote J, Rufian S, Pons JA, Alamo JM, Millán O, Brunet M. Impact of donor and recipient CYP3A5 and ABCB1 genetic polymorphisms on tacrolimus dosage requirements and rejection in Caucasian Spanish liver transplant patients. J Clin Pharmacol. 2013 Jul 30. PMID: 23900887.
  65. Cousar JL, Conley YP, Willyerd FA, Sarnaik AA, Puccio AM, Empey PE, Kochanek PM, Bell MJ, Okonkwo DO, Clark RS. Influence of ATP-Binding Cassette Polymorphisms on Neurological Outcome After Traumatic Brain Injury. Neurocrit Care. 2013 Jul 30. PMID: 23896815.
  66. Boiso Moreno S, Zackrisson AL, Jakobsen Falk I, Karlsson L, Carlsson B, Tillmar A, Kugelberg FC, Ahlner J, Hägg S, Gréen H. ABCB1 gene polymorphisms are associated with suicide in forensic autopsies. Pharmacogenet Genomics. 2013 Jun 29. PMID: 23820292.
  67. Doxani C, Voulgarelis M, Zintzaras E. MDR1 mRNA expression and MDR1 gene variants as predictors of response to chemotherapy in patients with acute myeloid leukaemia: a meta-analysis. Biomarkers. 2013 Jun 27. PMID: 23805980.
  68. Noordam R, Aarts N, Hofman A, van Schaik RH, Stricker BH, Visser LE. Association Between Genetic Variation in the ABCB1 Gene and Switching, Discontinuation, and Dosage of Antidepressant Therapy: Results From the Rotterdam Study. J Clin Psychopharmacol. 2013 Jun 13. PMID: 23771194.
  69. Wu H, Kang H, Liu Y, Xiao Q, Zhang Y, Sun M, Liu D, Wang Z, Zhao H, Yao W, Jia T, Wang E, Zheng Z, Wei M. Association of ABCB1 genetic polymorphisms with susceptibility to colorectal cancer and therapeutic prognosis. Pharmacogenomics. 2013 Jun;14(8):897-911. PMID: 23746184.
  70. Dickens D, Owen A, Alfirevic A, Pirmohamed M. ABCB1 single nucleotide polymorphisms (1236C>T, 2677G>T, and 3435C>T) do not affect transport activity of human P-glycoprotein. Pharmacogenet Genomics. 2013 Jun;23(6):314-23. PMID: 23619510.
  71. Chaturvedi P, Tulsyan S, Agarwal G, Lal P, Agarwal S, Mittal RD, Mittal B. Influence of ABCB1 genetic variants in breast cancer treatment outcomes. Cancer Epidemiol. 2013 May 22. PMID: 23707158.
  72. Wang LH, Song YB, Zheng WL, Jiang L, Ma WL. The association between polymorphisms in the MDR1 gene and risk of cancer: a systematic review and pooled analysis of 52 case--control studies. Cancer Cell Int. 2013 May 20;13(1):46. PMID: 23687985.
  73. Choong E, Polari A, Kamdem RH, Gervasoni N, Spisla C, Sirot EJ, Bickel GG, Bondolfi G, Conus P, Eap CB. Pharmacogenetic Study on Risperidone Long-Acting Injection: Influence of Cytochrome P450 2D6 and Pregnane X Receptor on Risperidone Exposure and Drug-Induced Side-Effects. J Clin Psychopharmacol. 2013 Apr 19. PMID: 23609392.
  74. Quaglia M, Terrazzino S, Boldorini R, Stratta P, Genazzani AA. Severe acute nephrotoxicity in a kidney transplant patient despite low tacrolimus levels: a possible interaction between donor and recipient genetic polymorphisms. J Clin Pharm Ther. 2013 Apr 9. PMID: 23574377.
  75. Cortejoso L, García MI, García-Alfonso P, González-Haba E, Escolar F, Sanjurjo M, López-Fernández LA. Differential toxicity biomarkers for irinotecan- and oxaliplatin-containing chemotherapy in colorectal cancer. Cancer Chemother Pharmacol. 2013 Mar 31. PMID: 23543295.
  76. Fukudo M, Ikemi Y, Togashi Y, Masago K, Kim YH, Mio T, Terada T, Teramukai S, Mishima M, Inui KI, Katsura T. Population Pharmacokinetics/Pharmacodynamics of Erlotinib and Pharmacogenomic Analysis of Plasma and Cerebrospinal Fluid Drug Concentrations in Japanese Patients with Non-Small Cell Lung Cancer. Clin Pharmacokinet. 2013 Mar 27. PMID: 23532985.
  77. Bellusci CP, Rocco C, Aulicino P, Mecikovsky D, Curras V, Hegoburu S, Bramuglia GF, Bologna R, Sen L, Mangano A. Influence of MDR1 C1236T polymorphism on lopinavir plasma concentration and virological response in HIV-1-infected children. Gene. 2013 Mar 22. PMID: 23528223.
  78. Karlsson L, Green H, Zackrisson AL, Bengtsson F, Jakobsen Falk I, Carlsson B, Ahlner J, Kugelberg FC. ABCB1 gene polymorphisms are associated with fatal intoxications involving venlafaxine but not citalopram. Int J Legal Med. 2013 Mar 21. PMID: 23515680.
  79. Zhang Y, Li JL, Fu Q, Wang XD, Liu LS, Wang CX, Xie W, Chen ZJ, Shu WY, Huang M. Associations of ABCB1, NFKB1, CYP3A, and NR1I2 polymorphisms with cyclosporine trough concentrations in Chinese renal transplant recipients. Acta Pharmacol Sin. 2013 Mar 18. PMID: 23503472.
  80. Khabour OF, Alzoubi KH, Al-Azzam SI, Mhaidat NM. Frequency of MDR1 single nucleotide polymorphisms in a Jordanian population, including a novel variant. Genet Mol Res. 2013 Mar 13;12(1):801-8. PMID: 23546964.
  81. Beuselinck B, Karadimou A, Lambrechts D, Claes B, Wolter P, Couchy G, Berkers J, Paridaens R, Schöffski P, Méjean A, Verkarre V, Lerut E, de la Taille A, Tourani JM, Bigot P, Linassier C, Négrier S, Berger J, Patard JJ, Zucman-Rossi J, Oudard S. Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib. Br J Cancer. 2013 Mar 5;108(4):887-900. PMID: 23462807.
  82. Zhou Q, Chen QX, Ruan ZR, Yuan H, Xu HM, Zeng S. CYP2C9*3(1075A > C), ABCB1 and SLCO1B1 genetic polymorphisms and gender are determinants of inter-subject variability in pitavastatin pharmacokinetics. Pharmazie. 2013 Mar;68(3):187-94. PMID: 23556337.
  83. Omoumi A, Wang Z, Yeow V, Wu-Chou YH, Chen PK, Ruczinski I, Cheng J, Cheah FS, Lee CG, Beaty TH, Chong SS. Fetal polymorphisms at the ABCB1-transporter gene locus are associated with susceptibility to non-syndromic oral cleft malformations. Eur J Hum Genet. 2013 Feb 27. PMID: 23443032.
  84. Zhou Q, Ruan ZR, Yuan H, Xu DH, Zeng S. ABCB1 gene polymorphisms, ABCB1 haplotypes and ABCG2 c.421c > A are determinants of inter-subject variability in rosuvastatin pharmacokinetics. Pharmazie. 2013 Feb;68(2):129-34. PMID: 23469685.
  85. Yoon SH, Cho JH, Kwon O, Choi JY, Park SH, Kim YL, Yoon YR, Won DI, Kim CD. CYP3A and ABCB1 Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Tacrolimus and Its Metabolites (M-I and M-III). Transplantation. 2013 Jan 29. PMID: 23364483.
  86. Dogruer D, Tug E, Bes C, Soy M. Lack of an effect of CYP3A4 and MDR1 gene polymorphisms on colchicine pharmacogenetics in the treatment of Familial Mediterranean fever. Genet Mol Res. 2013 Jan 24;12(AOP). PMID: 23408444.
  87. Yang J, Wang ZG, Cai HQ, Li YC, Xu YL. Effect of Variation of ABCB1 and ABCC3 Genotypes on the Survival of Bone Tumor Cases after Chemotherapy. Asian Pac J Cancer Prev. 2013;14(8):4595-4598. PMID: 24083708.
  88. Fountzilas G, Kotoula V, Pectasides D, Kouvatseas G, Timotheadou E, Bobos M, Mavropoulou X, Papadimitriou C, Vrettou E, Raptou G, Koutras A, Razis E, Bafaloukos D, Samantas E, Pentheroudakis G, Skarlos DV. Ixabepilone Administered Weekly or Every Three Weeks in HER2-Negative Metastatic Breast Cancer Patients; A Randomized Non-Comparative Phase II Trial. PLoS One. 2013;8(7):e69256. PMID: 23935969.
  89. Llaudó I, Colom H, Giménez-Bonafé P, Torras J, Caldés A, Sarrias M, Cruzado JM, Oppenheimer F, Sánchez-Plumed J, Gentil MA, Ekberg H, Grinyó JM, Lloberas N. Do drug transporter (ABCB1) SNPs and P-glycoprotein function influence cyclosporine and macrolides exposure in renal transplant patients? Results of the pharmacogenomic substudy within the symphony study. Transpl Int. 2012 Dec 7. PMID: 23216707.
  90. . [Pharmacogenetic criteria drug-resistence epilepsy]. Lik Sprava. 2012 Dec(8):71-4. PMID: 23786015.
  91. Kim YO, Kim SY, Yun DH, Lee SW. Association between ABCB1 Polymorphisms and Ischemic Stroke in Korean Population. Exp Neurobiol. 2012 Dec;21(4):164-71. PMID: 23319877.
  92. Wang YY, Zhang M, Lu FM, Jiao Z, Qiu XY. CYP3A4 genetic polymorphisms predict cyclosporine-related clinical events in Chinese renal transplant recipients. Chin Med J (Engl). 2012 Dec;125(23):4233-8. PMID: 23217392.
  93. Ozhan G, Kara M, Sari FM, Yanar HT, Ercan G, Alpertunga B. Associations Between The Functional Polymorphisms in The ABCB1 Transporter Gene and Colorectal Cancer Risk: A Case-Control Study in Turkish Population. Toxicol Mech Methods. 2012 Nov 29. PMID: 23193993.
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